OUR RESEARCH

Our research focuses on the cell signaling events that drive the propagation of the parasiteToxoplasma gondii. This remarkable parasite infects any warm blooded animal, can invade any nulceated cell, is found everywhere in the world, and infects a third of the world population. Toxoplasma can cause birth defects, and opportunistic disease in HIV/AIDS, cancer and organ transplant patients. A great part of the pathogenesis associated with toxoplasmosis is due to the repeating cycles of cell invasion, replication and egress that drive its propagation through an infected individual. Our lab is interested in the signaling pathways that regulate various aspects of this lytic cycle. Given that events such as invasion and egress are essential for parasite survival and that Toxoplasma uses some unique signaling molecules our studies aim at discovering novel targets for the development of much needed anti-parasitic drugs.  

LAB NEWS

New publication!
Graduate student Kaice LaFavers publishes her work on the role of a vacuole protein on calcium regulated egress in Cellular Microbiology.
Click here to READ IT! 
New publication!
In collaboration with the laboratory of Dr. Travis Jerde we have discovered that Toxoplasma infects and causes inflammation in the prostate of mice.
Click here to READ IT! 
Congratulations
Dr. Gaji has been awarded a Showalter grant for his proposal titled "ole of a unique plant like nuclear kinase in molecular pathogenesis of Toxoplasma gondii."
Congratulations
Congratulations to our new PhD graduates Kaice LaFavers and Joe Varberg.
Position Available
We are looking for a talented post-doctoral fellow to join our team and work on calcium signaling in Toxoplasma. Interested candidates please send cover letter, CV and name of 3 references to garrizab at iu.edu